BDBM50336640 (nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester::2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester::Adalat::Adalat CC::Afeditab cr::BAY-A-1040::NIFEDIPINE::Nefidipine::Procardia::Procardia XL::dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1ccccc1[N+]([O-])=O
InChI Key InChIKey=OSUCQKNXQBPLDG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50336640
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
University of Arizona
Curated by PDSP Ki Database
University of Arizona
Curated by PDSP Ki Database
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
University of Arizona
Curated by PDSP Ki Database
University of Arizona
Curated by PDSP Ki Database
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
University of Arizona
Curated by PDSP Ki Database
University of Arizona
Curated by PDSP Ki Database
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of porcine cardiac sarcolemma membrane vesiclesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
University of Arizona
Curated by PDSP Ki Database
University of Arizona
Curated by PDSP Ki Database
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
University of Arizona
Curated by PDSP Ki Database
University of Arizona
Curated by PDSP Ki Database
Affinity DataKi: 3.5nMAssay Description:Inhibition of [3H](+)-PN200-110 binding to L-type calcium channel 1,4-DHP binding site of rat ventricular myocytesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
University of Arizona
Curated by PDSP Ki Database
University of Arizona
Curated by PDSP Ki Database
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
University of Arizona
Curated by PDSP Ki Database
University of Arizona
Curated by PDSP Ki Database
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
University of Arizona
Curated by PDSP Ki Database
University of Arizona
Curated by PDSP Ki Database
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKd: 0.400nMAssay Description:Displacement of [3H]nitrendipine from dihydropyridine receptor of guinea pig myocardial membranesMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Alter
Curated by ChEMBL
Alter
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Blockade of calcium-evoked contractions in depolarized aortic stripsMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(RAT)
University of Arizona
Curated by PDSP Ki Database
University of Arizona
Curated by PDSP Ki Database
Affinity DataIC50: 1.40nMAssay Description:Inhibition of rat Cav1.2 channel in rat mesenteric artery assessed as relaxation of 70 mM K+ induced contractionMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Oryctolagus cuniculus)
Alter
Curated by ChEMBL
Alter
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]nitrendipine binding to calcium channels in Rabbit cardiac muscle.More data for this Ligand-Target Pair